The Indian stock market ended lower on September 22 2025 as weakness in IT shares weighed on the benchmarks. The Nifty 50 settled at 25200 down 430 points while the Sensex also declined sharply led by selling in technology heavyweights.

Sector-wise performance showed deep losses in IT with the index falling 2.7 percent as Tech Mahindra TCS Infosys and Wipro ended among the top Nifty losers. Pharma stocks also slipped by 1 percent with Cipla under pressure. In contrast, buying interest was seen in select pockets — the power index jumped 2 percent, oil and gas gained 0.7 percent, and realty added 0.4 percent.

On the broader market front, the BSE Midcap and Smallcap indices fell 0.5 percent each, reflecting broad-based weakness. Among individual performers, Adani Enterprises, Bajaj Auto, Adani Ports, UltraTech Cement, and Eternal stood out as the top gainers of the session, providing some cushion to the indices.

Overall, the market sentiment remained cautious as investors booked profits in IT counters while rotating into defensives and power-related stocks. Analysts suggest that global cues, sector-specific earnings outlook, and macroeconomic signals will continue to drive market direction in the near term.